Welcome to The Darfeuille Lab

Main objectives of the D-lab are the identification and characterization of small non-coding RNAs associated with the infection by the major gastric pathogen Helicobacter pylori. We try to understand the molecular and biochemical basis of RNA-based regulation of important genes involved in the pathogenicity and/or metabolism of this bacterium. In collaboration with RNA chemists, we also search for small compounds able to interfere with the biogenesis and the regulation of small RNAs. We hope that this research will help for the development of alternative strategies to fight against drug resistance both in the field of cancer and bacterial infections (antibiotic resistance).

Discover our lab

Our research


Our papers


Meet the team


News !

Nicolas Fix (Master MIMU, University of Bordeaux) is joigning the D-lab for a 6 month internship to defend his master degree in June 2017 ! His project will aim at developing an efficient tool to predict TA systems in bacteria. Welcome Nicolas !...

Sara Masachis Gelo (recruited in the EU Research-Training Network MetaRNA) recently joined the D-lab to start her PhD. She will engeneer RNA-based expression systems to monitor metabolic changes in living cells. Please find more infos about Sara: https://metarna.wordpress.com/2016/01/09/meet-the-fellows/  ...

They didn't know it was impossible so they did it ! Mark Twain

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