After having defended his PhD thesis in the lab of Dr. JJ. Toulmé (Targeting HIV-1 replication with RNA aptamers), Fabien went to the lab of Pr. G. Wagner (ICM, Uppsala, Sweden) to work on small regulatory RNA in E. coli. In 2006, he obtained a researcher position at the ARNA laboratory (University of Bordeaux) to search for small regulatory RNA in the gastric pathogen H. pylori. Since 2011, he is also the team leader of the STRAMES team, one of the ARNA lab team. DARFEUILLE_CV
Isabelle worked in the field of RNA decay, RNA helicases and ribosome biogenesis in E. coli (group of M. Dreyfus, at the Ecole Normale Supérieure in Paris). She also worked on RNA helicase and translation in the yeast S. cerevisiae (group of P. Linder in Geneva). She is now studying the role of some antisense RNAs in H. pylori.
Sara’s project aims understanding the role of mRNA folding dynamics as a key actor regulating type I toxin-antitoxin (TAs) systems expression. Keeping in mind the minimalistic physical compartmentalization present in bacteria and the interdependent existence aspect TA systems components hold as drivers of her quest.