Fabien Darfeuille

Group leader (CR1 INSERM)

After having defended his PhD thesis in the lab of Dr. JJ. Toulmé (Targeting HIV-1 replication with RNA aptamers), Fabien went to the lab of Pr. G. Wagner (ICM, Uppsala, Sweden) to work on small regulatory RNA in E. coli. In 2006, he obtained a researcher position at the ARNA laboratory (University of Bordeaux) to search for small regulatory RNA in the gastric pathogen H. pylori. Since 2011, he is also the team leader of the STRAMES team, one of the ARNA lab team. DARFEUILLE_CV

Cathy Staedel

Researcher (CR1 INSERM)

Cathy is our expert in miRNA research. She’s studying their expression in response to H. pylori infection and their deregulation in gastric cancer.

Isabelle Iost

Researcher (CR1 CNRS)

Isabelle worked in the field of RNA decay, RNA helicases and ribosome biogenesis in E. coli (group of M. Dreyfus, at the Ecole Normale Supérieure in Paris). She also worked on RNA helicase and translation in the yeast S. cerevisiae (group of P. Linder in Geneva). She is now studying the role of some antisense RNAs in H. pylori.

Sandrine Chabas

Engineer (IE INSERM)

Sandrine is our lab manager (the Tinkerbell fairy of the D-Lab)

Fanny Boissier

Engineer (IE Univ. Bordeaux)

Fanny is our expert in protein expression and purification. Her project studies how H. pylori’s RNases work and interact with each other from a structural biology perspective.

Delphine Bronesky

Postdoctoral researcher (ANR grant)

Delphine’s project aims at deciphering ways of activating toxin expression with the final goal of using it as an alternative to antibiotics to treat H. pylori infections

Sara Masachis-Gelo

Graduate Student (MC ITN MetaRNA)

Sara’s project aims understanding the role of mRNA folding dynamics as a key actor regulating type I toxin-antitoxin (TAs) systems expression. Keeping in mind the minimalistic physical compartmentalization present in bacteria and the interdependent existence aspect TA systems components hold as drivers of her quest.

Former members

  • Jérémy Reignier (PhD, 2007-2010) now in Merck Serono, Switzerland
  • Cédric Belair (PhD, 2006-2010) now in Sandra Wolin lab, Yale University, USA
  • Jessica Baud (PhD, 2008-2012) now in Institut Bergonié, Bordeaux, France
  • Dursun Nizam Korkut (PhD, 2012-2015)
  • Jaydip Ghosh (Postdoc, 2007-2009)
  • Maya Ayach (Postdoc, 2013-2015)
  • Claire Lays (Postdoc, 2013-2015), now in CIRI, Lyon, France
  • Hélène Arnion (Master, 2008-2013)
  • Marion Faucher (Master, 2014-2015)
  • Nicolas Fix (Master, 2016-2017)
  • Tifenn Desroziers (Master, 2017-2018)

Lab Life