Want to identify the toxicity determinants hidden within your type I TA system? Try out our method! FASTBAC-Seq: Functional AnalysiS of Toxin-Antitoxin Systems in BACteria by Deep Sequencing  https://www.sciencedirect.com/science/article/pii/S0076687918303318...

We are pleased to share with you that our latest review article 'Type I Toxin-Antitoxin Systems: Regulating Toxin Expression via Shine-Dalgarno Sequence Sequestration and Small RNA Binding' is now available on the ASMscience website!  ...

Delphine Bronesky (PhD student, Université de Strasbourg, Architecture de l'ARN et réactivité, IBMC, under the supervision of P. Romby and I. Caldelari) has recently joined the lab ! She will start a new project in the group, that consists in turning on the expression of toxin-antitoxin...

The D-Lab is just back from the traditional  3-days Lab retreat in the Pyrénées ! A great occasion to get to know about the last and most exciting research going on in each of the teams composing this astonishing Unit ! .. and, of course, have some fun !  ...

  Our lastest paper is now published online in Nucleic Acids Research ! Figure 8   Please visit NAR Advance Access A new toxin antitoxin system was discovered in the human gastric pathogen Helicobacter pylori. This new TA system is actually conserved in many epsilon proteobacteria. It shares striking similarities with other TA previously described in Escherichia coli like hok/sok and ldr/rdl TA systems.